Term	Overlap	P-value	Adjusted P-value	Odds Ratio	Combined Score	Genes	highlighted_yellow_enriched_in_zebrafish
Ras signaling pathway	48/232	2.43e-08	7.3e-06	2.718257855	47.65598198	SHC1;PDGFA;PIK3CD;PIK3R1;RASAL2;EFNA5;PLD1;RASGRP2;ETS1;FGF2;IGF1R;RASSF1;NRAS;PAK1;GNG2;AKT2;RASSF5;PDGFC;NTF3;ABL1;AKT1;SHOC2;IKBKG;PAK3;PRKACB;RALGDS;MAPK3;PDGFRA;NTRK2;RALBP1;PLA2G12A;MAP2K2;BAD;IGF2;VEGFB;IGF1;RHOA;VEGFA;TIAM1;GNB2;RASA1;GRB2;CALM1;RGL1;RAPGEF5;RGL2;FGFR2;BCL2L1	FALSE
Pathways in cancer	84/531	1.37e-07	1.37e-05	1.970548989	31.14084317	GSK3B;HSP90AB1;ARAF;PIK3CD;FGF2;ETS1;GLI3;BBC3;GLI2;IGF1R;RASSF1;CCND3;EDNRB;CCND2;MECOM;AKT2;MYC;RASSF5;AKT1;EP300;IKBKG;PRKACB;APC2;PDGFRA;HSP90AA1;RALBP1;MAP2K2;DAPK1;TPM3;PLEKHG5;NCOA4;WNT5A;AXIN2;RHOA;RUNX1;PLCB3;PLCB4;RARA;ARHGEF1;CAMK2D;CTBP2;CAMK2A;CUL1;PDGFA;XIAP;PIK3R1;PLD1;RASGRP2;HSP90B1;DLL3;RXRB;NRAS;BCL2L11;GNG2;WNT11;ABL1;E2F3;RALGDS;RUNX1T1;MAPK3;SMAD2;TCF7L2;TGFB2;EGLN2;TXNRD2;BAD;TXNRD1;PTCH1;IGF2;VEGFB;IGF1;EPOR;VEGFA;BMP4;CDK6;APC;GNAQ;GNB2;MDM2;GNAS;GRB2;CALM1;FGFR2;BCL2L1	FALSE
Wnt signaling pathway	36/166	4e-07	2.18e-05	2.874248643	42.34479673	GSK3B;CAMK2D;CTBP2;CTNND2;CHD8;CAMK2A;CUL1;PRICKLE2;PRICKLE1;PPP3CA;CCND3;CCND2;WNT11;SOX17;MYC;EP300;BTRC;PRKACB;TLE4;APC2;TLE3;TCF7L2;TLE1;WNT5A;NFATC2;NFATC1;AXIN2;RHOA;VANGL1;PLCB3;SFRP2;VANGL2;PLCB4;DAAM1;APC;CSNK2B	TRUE
Proteoglycans in cancer	41/205	6.42e-07	2.75e-05	2.597382048	37.0346498	DDX5;CAMK2D;CAMK2A;ARAF;PIK3CD;PIK3R1;FGF2;ACTB;IGF1R;NRAS;PAK1;WNT11;AKT2;MYC;AKT1;FLNA;DROSHA;PRKACB;MAPK3;VAV3;SMAD2;TGFB2;MAP2K2;CAV1;PTCH1;WNT5A;IGF2;ANK2;ANK3;IGF1;ANK1;RHOA;VEGFA;COL1A1;TIAM1;COL1A2;MDM2;PDCD4;GRB2;ARHGEF1;PPP1R12B	FALSE
Transcriptional misregulation in cancer	39/192	7.93e-07	2.83e-05	2.646878522	37.18124102	DDX5;LDB1;JMJD1C;PDGFA;SIX1;MLLT3;AFF1;IGF1R;HOXA10;RXRB;HOXA9;FUT8;CCND2;SIN3A;MYC;PROM1;RUNX1T1;MEF2C;BCL11B;EYA1;IGFBP3;LMO2;PBX3;HMGA2;IGF1;ETV4;KLF3;RUNX2;PBX1;RUNX1;ETV6;MAF;NCOR1;EWSR1;WT1;MDM2;RARA;TCF3;BCL2L1	FALSE
PI3K-Akt signaling pathway	60/354	8.49e-07	2.83e-05	2.128313804	29.75305726	YWHAE;GSK3B;HSP90AB1;IRS1;YWHAB;PIK3CD;FGF2;IGF1R;GHR;CCND3;CCND2;AKT2;MYC;AKT1;ITGB8;IKBKG;MAGI1;PDGFRA;HSP90AA1;MAP2K2;MAGI2;PPP2R5C;YWHAZ;CREB3;COL6A3;SGK3;SGK1;PDGFA;PIK3R1;EFNA5;FOXO3;HSP90B1;THBS3;NRAS;BCL2L11;GNG2;PDGFC;NTF3;MCL1;MAPK3;NTRK2;BAD;IGF2;VEGFB;IGF1;PPP2R3A;EPOR;VEGFA;COL1A1;COL1A2;CDK6;PPP2R2B;GNB2;PPP2R2D;COL9A1;MDM2;GRB2;PKN1;FGFR2;BCL2L1	FALSE
Rap1 signaling pathway	41/210	1.24e-06	3.68e-05	2.519838487	34.27584674	PDGFA;PIK3CD;PIK3R1;EFNA5;RASGRP2;FGF2;ACTB;RAP1GAP;IGF1R;NRAS;SIPA1L1;AKT2;RASSF5;PDGFC;AKT1;RALGDS;MAPK3;VAV3;MAGI1;PDGFRA;MAP2K2;MAGI2;VEGFB;ARAP3;IGF1;RHOA;VEGFA;TIAM1;PLCB3;PLCB4;PARD3;GNAQ;GNAS;EVL;TLN2;PFN1;CALM1;RAPGEF5;RAPGEF6;FGFR2;BCAR1	FALSE
Neurotrophin signaling pathway	28/119	1.38e-06	3.68e-05	3.18587181	42.97914572	YWHAE;GSK3B;CAMK2D;IRS1;MAGED1;SHC1;CAMK2A;PIK3CD;PIK3R1;FOXO3;RPS6KA3;NRAS;MAPK7;IRAK2;AKT2;ARHGDIB;RPS6KA1;NTF3;ABL1;AKT1;SH2B2;MAPK3;NTRK2;MAP2K2;BAD;RHOA;GRB2;CALM1	FALSE
Axon guidance	37/182	1.47e-06	3.68e-05	2.64781662	35.5538796	ROBO2;GSK3B;CAMK2D;SEMA3A;CAMK2A;PIK3CD;PIK3R1;EFNA5;PPP3CA;ABLIM1;NRAS;PAK1;RGS3;ABLIM3;DPYSL2;ABL1;SLIT3;SRGAP3;SLIT2;PAK3;MAPK3;SEMA6D;PTCH1;LIMK2;SEMA4B;WNT5A;SEMA4C;NFATC2;UNC5C;SSH2;RHOA;SSH1;RGMA;PARD3;RASA1;PLXNB2;PLXNB1	FALSE
Thyroid hormone signaling pathway	28/121	1.97e-06	4.55e-05	3.117014548	40.94770399	PFKFB2;GSK3B;THRA;PIK3CD;GATA4;PIK3R1;ACTB;RXRB;NRAS;MED13;SIN3A;AKT2;MYC;AKT1;EP300;PRKACB;MAPK3;NCOA2;MAP2K2;BAD;BMP4;RCAN1;PLCB3;NCOR1;PLCB4;RCAN2;MDM2;PFKM	FALSE
Focal adhesion	39/201	2.61e-06	5.6e-05	2.498584504	32.12054492	GSK3B;SHC1;PDGFA;XIAP;PIK3CD;PIK3R1;ACTB;MYLK3;MYLK;IGF1R;THBS3;PAK1;CCND3;CCND2;AKT2;PDGFC;AKT1;FLNA;ITGB8;PAK3;MAPK3;VAV3;PDGFRA;BAD;CAV1;VEGFB;IGF1;PARVB;RHOA;VEGFA;COL1A1;MYLPF;COL1A2;COL9A1;COL6A3;GRB2;TLN2;PPP1R12B;BCAR1	TRUE
MAPK signaling pathway	50/294	6.14e-06	0.000108	2.130602357	25.56775584	ARAF;ARRB1;FGF2;IGF1R;RPS6KA3;PPP3CA;MECOM;AKT2;MYC;RPS6KA1;AKT1;IKBKG;PRKACB;PDGFRA;MEF2C;DUSP3;MAP2K2;MAPK8IP1;DUSP7;CACNB3;RASA1;MAPKAPK5;PDGFA;CACNA1A;EFNA5;RASGRP2;CACNA1H;CACNA1G;NRAS;PAK1;MAPK7;PDGFC;NTF3;FLNA;MAPK3;HSPA8;NTRK2;TGFB2;IGF2;VEGFB;NFATC1;IGF1;VEGFA;TAOK3;GRB2;PTPN7;PTPN5;FGFR2;MAP3K11;MAP3K12	FALSE
AMPK signaling pathway	26/120	1.6e-05	0.000252	2.860154629	31.59220663	PFKFB2;IRS1;CAB39L;PIK3CD;PRKAG2;PIK3R1;FOXO3;ADIPOR2;ACACA;IGF1R;AKT2;HNF4A;LEPR;AKT1;CD36;SREBF1;IGF1;PPP2R5C;PPP2R3A;EEF2;CREB3;TBC1D1;PPP2R2B;AKT1S1;PPP2R2D;PFKM	FALSE
Hippo signaling pathway	31/163	4e-05	0.000601	2.430305631	24.60811736	YWHAE;GSK3B;YWHAB;AFP;ACTB;BBC3;GLI2;CCND3;RASSF1;PAK1;CCND2;WNT11;MYC;BTRC;TEAD1;TEAD2;SMAD2;APC2;TCF7L2;TGFB2;WNT5A;SCRIB;AXIN2;YWHAZ;BMP4;DLG2;DLG3;APC;PPP2R2B;PARD3;PPP2R2D	FALSE
Parathyroid hormone synthesis, secretion and action	23/106	4.71e-05	0.000642	2.862296567	28.51976789	MEF2C;PDE4D;ARAF;ARRB1;GATA3;PTH1R;PLD1;RUNX2;RHOA;NR4A2;RXRB;AKAP13;CREB3;PLCB3;PLCB4;MMP16;MMP15;GNAQ;GNAS;PDE4B;ARHGEF1;PRKACB;MAPK3	FALSE
Signaling pathways regulating pluripotency of stem cells	28/143	5.43e-05	0.000708	2.517656991	24.72780425	GSK3B;PIK3CD;PIK3R1;FGF2;IGF1R;NRAS;WNT11;AKT2;MYC;AKT1;JARID2;MAPK3;SMAD2;APC2;MAP2K2;PCGF5;PCGF2;WNT5A;LIFR;PAX6;IGF1;AXIN2;SMAD5;BMP4;APC;GRB2;TCF3;FGFR2	FALSE
cGMP-PKG signaling pathway	31/167	6.47e-05	0.000809	2.358304449	22.74774962	IRS1;GATA4;MYLK3;SLC8A1;MYLK;SLC8A2;PPP3CA;EDNRB;AKT2;KCNMB2;AKT1;KCNMB4;PRKG1;MAPK3;MEF2C;MAP2K2;BAD;PDE2A;NFATC2;NFATC1;ATP2B1;RHOA;CREB3;PLCB3;PLCB4;GNAQ;KCNMA1;PDE3A;VDAC2;PDE5A;CALM1	FALSE
Regulation of actin cytoskeleton	37/218	9.84e-05	0.001093211	2.116954539	19.53225475	ARAF;PDGFA;PIK3CD;PIK3R1;IQGAP2;FGF2;ACTB;MYLK3;MYLK;NRAS;PAK1;PDGFC;MYH14;ITGB8;PAK3;MYH10;MAPK3;APC2;VAV3;PDGFRA;GSN;MAP2K2;LIMK2;SSH2;RHOA;SSH1;MYLPF;TIAM1;APC;SPATA13;ARHGEF1;PFN1;ARHGEF7;PPP1R12B;FGFR2;BCAR1;ARHGEF6	FALSE
ErbB signaling pathway	19/85	0.000138	0.001475547	2.969567837	26.40036193	GSK3B;CAMK2D;MAP2K2;SHC1;BAD;CAMK2A;ARAF;PIK3CD;NRG1;PIK3R1;NRAS;PAK1;AKT2;MYC;ABL1;AKT1;GRB2;PAK3;MAPK3	TRUE
Insulin signaling pathway	26/137	0.000168	0.001679824	2.419841404	21.03241717	GSK3B;IRS1;SHC1;ARAF;INPPL1;PIK3CD;PRKAG2;PIK3R1;ACACA;HK1;NRAS;SOCS1;AKT2;AKT1;PRKACB;SH2B2;MAPK3;SREBF1;MAP2K2;BAD;SORBS1;PPP1R3F;PPP1R3B;PRKAR1A;GRB2;CALM1	FALSE
Acute myeloid leukemia	16/67	0.000203	0.001959771	3.233347792	27.49872648	TCF7L2;MAP2K2;BAD;ARAF;PIK3CD;PIK3R1;RUNX1;NRAS;AKT2;MYC;RARA;AKT1;GRB2;IKBKG;MAPK3;RUNX1T1	FALSE
Cell cycle	24/124	0.000216	0.002024374	2.47808547	20.9163824	SMAD2;CDKN1C;YWHAE;GSK3B;TGFB2;MCM7;YWHAB;CUL1;SMC1A;YWHAZ;CDC14B;MAD2L2;ORC4;CCND3;CCND2;CDK6;STAG2;TFDP1;TFDP2;MYC;ABL1;MDM2;EP300;E2F3	TRUE
Cellular senescence	28/156	0.000257	0.002337034	2.260333381	18.68424966	PIK3CD;GATA4;PIK3R1;FOXO3;ETS1;PPP3CA;CCND3;NRAS;CCND2;AKT2;MYC;RASSF5;AKT1;E2F3;CAPN1;BTRC;MAPK3;SMAD2;TGFB2;MAP2K2;IGFBP3;NFATC2;NFATC1;HIPK1;CDK6;MDM2;VDAC2;CALM1	FALSE
Growth hormone synthesis, secretion and action	23/119	0.000296	0.002608932	2.472920226	20.09553445	GSK3B;MAP2K2;IRS1;SHC1;IGFBP3;PIK3CD;PIK3R1;IGF1;GHR;CREB3;PLCB3;NRAS;SOCS1;PLCB4;AKT2;GNAQ;GNAS;AKT1;EP300;GRB2;PRKACB;BCAR1;MAPK3	FALSE
Estrogen signaling pathway	25/137	0.000415	0.003553921	2.304553877	17.94818427	HSP90AB1;SHC1;PIK3CD;PIK3R1;HSP90B1;NRAS;AKT2;AKT1;PRKACB;MAPK3;HSPA8;NCOA2;HSP90AA1;GABBR1;MAP2K2;KRT10;CREB3;PLCB3;PLCB4;GNAQ;KRT14;GNAS;RARA;GRB2;CALM1	FALSE
FoxO signaling pathway	24/131	0.000504	0.004203975	2.315073089	17.57600762	TGFB2;MAP2K2;IRS1;FOXG1;ARAF;PIK3CD;PRKAG2;PIK3R1;IGF1;FOXO3;IGF1R;NRAS;CCND2;BCL2L11;AKT2;CCNG2;CAT;MDM2;AKT1;EP300;GRB2;SGK3;SGK1;MAPK3	TRUE
Dopaminergic synapse	24/132	0.000566	0.004577189	2.293510605	17.15017458	GSK3B;CAMK2D;DDC;CAMK2A;CACNA1A;ARRB1;PPP2R5C;PPP2R3A;COMT;PPP3CA;CREB3;PLCB3;PLCB4;GNG2;PPP2R2B;AKT2;GNAQ;GNB2;PPP2R2D;GNAS;AKT1;CALM1;PRKACB;GRIA4	FALSE
Ubiquitin mediated proteolysis	25/140	0.00058	0.004577189	2.244063259	16.72470415	UBA7;UBE2D3;CUL1;NEDD4L;XIAP;KLHL13;RCHY1;SOCS1;BTRC;PIAS3;UBE2I;FBXW7;UBE2E3;HUWE1;SYVN1;UBE2E2;UBE4B;WWP2;MID1;PIAS2;MDM2;UBA1;TRIP12;UBE2M;CUL4B	FALSE
Long-term potentiation	15/67	0.000663	0.005097387	2.971121141	21.74637248	CAMK2D;MAP2K2;CAMK2A;ARAF;PPP3CA;RPS6KA3;PLCB3;NRAS;PLCB4;GNAQ;RPS6KA1;EP300;CALM1;PRKACB;MAPK3	FALSE
Relaxin signaling pathway	23/129	0.000964	0.00722767	2.238390209	15.54504151	SMAD2;MAP2K2;SHC1;VEGFB;PIK3CD;ARRB1;PIK3R1;VEGFA;COL1A1;CREB3;PLCB3;NRAS;EDNRB;COL1A2;PLCB4;GNG2;AKT2;GNB2;GNAS;AKT1;GRB2;PRKACB;MAPK3	FALSE
Oxytocin signaling pathway	26/154	0.0010848	0.007937575	2.09648638	14.31136619	CAMK2D;CAMK2A;PRKAG2;ACTB;MYLK3;MYLK;PPP3CA;NRAS;MAPK7;PRKACB;MAPK3;MEF2C;MAP2K2;NFATC2;NFATC1;EEF2;RHOA;RCAN1;CACNB3;MYL6;PLCB3;PLCB4;GNAQ;GNAS;CALM1;PPP1R12B	FALSE
GnRH secretion	14/64	0.00125972	0.008998001	2.882651558	19.24707743	GABBR1;MAP2K2;PIK3CD;ARRB1;PIK3R1;CACNA1H;CACNA1G;PLCB3;NRAS;PLCB4;AKT2;GNAQ;AKT1;MAPK3	FALSE
Vascular smooth muscle contraction	23/133	0.001474	0.010283747	2.156517913	14.06000718	PLA2G12A;MAP2K2;ARAF;MYLK3;RHOA;MYLK;MYL6;PLCB3;PLCB4;CALD1;GNAQ;KCNMB2;KCNMA1;GNAS;KCNMB4;MYH14;ARHGEF1;CALM1;PPP1R12B;PRKACB;MYH10;PRKG1;MAPK3	FALSE
Adrenergic signaling in cardiomyocytes	25/150	0.00161194	0.010990507	2.063397948	13.26830129	CAMK2D;CAMK2A;CREM;SLC8A1;SLC8A2;AKT2;AKT1;PRKACB;MAPK3;TPM3;TPM2;TPM1;PPP2R5C;ATP2B1;PPP2R3A;MYL4;CREB3;CACNB3;PLCB3;PLCB4;PPP2R2B;GNAQ;PPP2R2D;GNAS;CALM1	FALSE
Apelin signaling pathway	23/137	0.00220005	0.014348122	2.08039104	12.73048971	SMAD2;HDAC4;HDAC5;MEF2C;MAP2K2;SPHK2;PRKAG2;MYLK3;SLC8A1;MYLK;SLC8A2;MYL4;PLCB3;NRAS;PLCB4;GNG2;AKT2;GNAQ;GNB2;AKT1;CALM1;PRKACB;MAPK3	FALSE
mTOR signaling pathway	25/154	0.00233729	0.014611122	1.998974658	12.11131351	PRR5;GSK3B;IRS1;CAB39L;PIK3CD;SLC3A2;PIK3R1;IGF1R;RPS6KA3;NRAS;WNT11;AKT2;RPS6KA1;GRB10;AKT1;MAPK3;ATP6V1G2;MAP2K2;WNT5A;IGF1;RHOA;AKT1S1;GRB2;SGK1;LPIN2	FALSE
MicroRNAs in cancer	43/310	0.00233778	0.014611122	1.665592261	10.09108023	HDAC4;HDAC5;IRS1;SHC1;PDGFA;PIK3CD;PIK3R1;EFNA5;SLC7A1;RASSF1;NRAS;CCND2;BCL2L11;SOCS1;MAPK7;MYC;ABL1;IGF2BP1;EP300;E2F3;SOX4;MCL1;MAPK3;APC2;PDGFRA;TGFB2;MAP2K2;UBE2I;TPM1;DNMT3A;HMGA2;RHOA;VEGFA;FOXP1;ZEB2;HNRNPK;CDK6;MMP16;APC;FSCN1;MDM2;PDCD4;GRB2	FALSE
Human cytomegalovirus infection	33/225	0.00296728	0.017097663	1.774761956	10.32931178	GSK3B;PIK3CD;PIK3R1;AKAP13;PPP3CA;NRAS;GNG2;AKT2;MYC;AKT1;E2F3;IKBKG;PRKACB;MAPK3;PDGFRA;MAP2K2;NFATC2;NFATC1;RHOA;VEGFA;CREB3;PLCB3;PLCB4;CDK6;GNAQ;GNB2;GNAS;MDM2;GRB2;ARHGEF1;CALR;CALM1;BCAR1	FALSE
Platelet activation	21/124	0.00300253	0.017097663	2.101229332	12.20457106	GP1BB;PIK3CD;PIK3R1;RASGRP2;ACTB;MYLK3;RHOA;MYLK;COL1A1;PLCB3;COL1A2;PLCB4;AKT2;GNAQ;GNAS;AKT1;ARHGEF1;TLN2;PRKACB;PRKG1;MAPK3	FALSE
Central carbon metabolism in cancer	14/70	0.00307797	0.017097663	2.572946176	14.88059813	PDGFRA;MAP2K2;IDH1;PIK3CD;SIRT6;PIK3R1;HK1;NRAS;AKT2;MYC;AKT1;PFKM;FGFR2;MAPK3	FALSE
Prolactin signaling pathway	14/70	0.00307797	0.017097663	2.572946176	14.88059813	GSK3B;MAP2K2;GALT;SHC1;PIK3CD;PIK3R1;FOXO3;NRAS;CCND2;SOCS1;AKT2;AKT1;GRB2;MAPK3	FALSE
Gastric cancer	24/149	0.00313457	0.017097663	1.979733333	11.41368287	SMAD2;APC2;GSK3B;TCF7L2;TGFB2;MAP2K2;SHC1;WNT5A;ARAF;PIK3CD;PIK3R1;AXIN2;FGF2;RXRB;NRAS;WNT11;APC;AKT2;MYC;AKT1;GRB2;E2F3;FGFR2;MAPK3	FALSE
Melanogenesis	18/101	0.00329018	0.017625976	2.233697995	12.76963222	GSK3B;TCF7L2;CAMK2D;MAP2K2;WNT5A;CAMK2A;CREB3;PLCB3;NRAS;EDNRB;PLCB4;WNT11;GNAQ;GNAS;EP300;CALM1;PRKACB;MAPK3	FALSE
TGF-beta signaling pathway	17/94	0.00360423	0.018969647	2.273449592	12.78962335	TGIF1;SMAD2;TGFB2;TGIF2;CUL1;RGMB;LTBP1;SMAD5;RHOA;THSD4;RGMA;BMP4;TFDP1;MYC;EP300;PITX2;MAPK3	TRUE
Longevity regulating pathway	18/102	0.00367071	0.018986454	2.206984668	12.37537737	HSPA8;IRS1;EHMT2;PIK3CD;PRKAG2;PIK3R1;IGF1;FOXO3;ADIPOR2;IGF1R;CREB3;NRAS;AKT2;SESN1;AKT1S1;CAT;AKT1;PRKACB	FALSE
p53 signaling pathway	14/73	0.00458426	0.023210734	2.441715081	13.14894644	STEAP3;RRM2;IGFBP3;SHISA5;IGF1;RCHY1;BBC3;CCND3;CCND2;CDK6;SESN1;CCNG2;MDM2;BCL2L1	TRUE
Human papillomavirus infection	44/331	0.00467253	0.023210734	1.584705138	8.503613972	GSK3B;PIK3CD;PIK3R1;RBPJ;THBS3;NRAS;CCND3;CCND2;WNT11;AKT2;AKT1;EP300;ITGB8;IKBKG;PRKACB;MAPK3;APC2;MAGI1;TCF7L2;ATP6V1G2;MAP2K2;BAD;WNT5A;SCRIB;AXIN2;PPP2R5C;PPP2R3A;VEGFA;COL1A1;CREB3;COL1A2;CDK6;DLG2;DLG3;APC;PPP2R2B;PARD3;PPP2R2D;COL9A1;GNAS;MDM2;COL6A3;GRB2;MAML3	FALSE
Yersinia infection	22/137	0.00471952	0.023210734	1.971403826	10.55893561	VAV3;GSK3B;MAP2K2;WIPF1;NFATC2;PIK3CD;NFATC1;PIK3R1;ACTB;RHOA;RPS6KA3;AKT2;GNAQ;RPS6KA1;ELMO1;AKT1;ARHGEF1;IKBKG;PKN1;ARHGEF7;BCAR1;MAPK3	FALSE
B cell receptor signaling pathway	15/81	0.00480861	0.023267459	2.339079571	12.48448068	VAV3;GSK3B;MAP2K2;INPPL1;PIK3CD;NFATC2;NFATC1;PIK3R1;PPP3CA;NRAS;AKT2;AKT1;GRB2;IKBKG;MAPK3	FALSE
VEGF signaling pathway	12/059	0.00513883	0.024470627	2.626015966	13.84154509	PPP3CA;NRAS;MAP2K2;SPHK2;BAD;AKT2;PIK3CD;AKT1;NFATC2;PIK3R1;MAPK3;VEGFA	FALSE
cAMP signaling pathway	31/216	0.00538239	0.025229967	1.728975199	9.033242211	CAMK2D;CAMK2A;PIK3CD;PIK3R1;PLD1;GLI3;PAK1;AKT2;PDE4B;AKT1;EP300;SOX9;PRKACB;GRIA4;MAPK3;VAV3;GABBR1;MAP2K2;BAD;PTCH1;PDE4D;ARAP3;NFATC1;ATP2B1;RHOA;TIAM1;CREB3;FXYD1;PDE3A;GNAS;CALM1	FALSE
Glutamatergic synapse	19/114	0.0055179	0.02546721	2.059772727	10.71032124	SLC38A1;SLC1A2;CACNA1A;GRIK2;PLD1;PPP3CA;PLCB3;PLCB4;GNG2;GNAQ;GNB2;GNAS;DLGAP1;PRKACB;SLC38A2;SHANK3;GRIA4;SHANK1;MAPK3	FALSE
Phospholipase D signaling pathway	23/148	0.00590712	0.026486614	1.896164009	9.730349795	PDGFRA;MAP2K2;SHC1;SPHK2;PDGFA;PIK3CD;PIK3R1;PLD1;DGKZ;DNM1;RHOA;DNM3;PLCB3;NRAS;PLCB4;AKT2;PDGFC;GNAS;AKT1;GRB2;RALGDS;CYTH1;MAPK3	FALSE
Sphingolipid signaling pathway	19/119	0.0087672	0.038678832	1.956244318	9.266215961	MAP2K2;SGMS1;SPHK2;PIK3CD;PIK3R1;PPP2R5C;PPP2R3A;PLD1;RHOA;ACER2;PLCB3;NRAS;PLCB4;PPP2R2B;AKT2;GNAQ;PPP2R2D;AKT1;MAPK3	FALSE
Lipid and atherosclerosis	30/215	0.00905191	0.039356129	1.672245144	7.867544713	GSK3B;CAMK2D;HSP90AB1;CAMK2A;PIK3CD;PIK3R1;VLDLR;HSP90B1;RXRB;PPP3CA;NRAS;AKT2;AKT1;CD36;IKBKG;MAPK3;VAV3;HSPA8;HSP90AA1;HSPA5;BAD;NFATC2;APOA1;NFATC1;RHOA;PLCB3;PLCB4;ARHGEF1;CALM1;BCL2L1	FALSE
Autophagy	21/137	0.00964081	0.04131775	1.864408026	8.654116541	MAP2K2;IRS1;DAPK1;BAD;ATG9A;PIK3CD;PIK3R1;HMGB1;CFLAR;MTMR4;ZFYVE1;IGF1R;VMP1;NRAS;AKT2;AKT1S1;AKT1;ATG4A;PRKACB;BCL2L1;MAPK3	FALSE
Oocyte meiosis	20/129	0.01004713	0.042128677	1.889313674	8.69172702	YWHAE;CAMK2D;YWHAB;CAMK2A;CUL1;IGF1;PPP2R5C;SMC1A;YWHAZ;IGF1R;MAD2L2;RPS6KA3;PPP3CA;RPS6KA1;BTRC;CALM1;CPEB3;PRKACB;CPEB2;MAPK3	FALSE
T cell receptor signaling pathway	17/104	0.0101318	0.042128677	2.011024567	9.234778995	VAV3;GSK3B;MAP2K2;NFATC2;PIK3CD;NFATC1;PIK3R1;RHOA;PPP3CA;NRAS;PAK1;AKT2;AKT1;GRB2;IKBKG;PAK3;MAPK3	FALSE
Cushing syndrome	23/155	0.01025131	0.042128677	1.794915269	8.221339494	APC2;GSK3B;TCF7L2;CAMK2D;MAP2K2;WNT5A;CAMK2A;AIP;AXIN2;CACNA1H;PBX1;CACNA1G;CREB3;PLCB3;CDK6;PLCB4;WNT11;APC;GNAQ;GNAS;E2F3;PRKACB;MAPK3	FALSE
Circadian entrainment	16/97	0.01137649	0.045837652	2.032450299	9.097666055	CAMK2D;CAMK2A;CACNA1H;CACNA1G;PER1;PLCB3;PLCB4;GNG2;GNAQ;GNB2;GNAS;CALM1;PRKACB;PRKG1;GRIA4;MAPK3	FALSE
Chemokine signaling pathway	27/192	0.0115964	0.045837652	1.686425903	7.51650199	GSK3B;SHC1;PIK3CD;ARRB1;PIK3R1;FOXO3;RASGRP2;NRAS;PAK1;GNG2;AKT2;AKT1;IKBKG;PRKACB;MAPK3;VAV3;BAD;RHOA;TIAM1;PLCB3;PLCB4;PARD3;GNAQ;GNB2;ELMO1;GRB2;BCAR1	FALSE
Human T-cell leukemia virus 1 infection	30/219	0.01161221	0.045837652	1.636490693	7.291709233	TRRAP;XIAP;PIK3CD;PIK3R1;ETS1;PPP3CA;NRAS;CCND3;XPO1;CCND2;AKT2;MYC;AKT1;EP300;E2F3;IKBKG;PRKACB;MAPK3;SMAD2;TGFB2;MAP2K2;NFATC2;NFATC1;CREB3;CANX;VDAC2;TLN2;CALR;TCF3;BCL2L1	FALSE